A NETWORK PROCESSING NODE FOR LIGHT UNMANNED AIRCRAFT

Over the last decade, research into unmanned and autonomous vehicles has greatly increased. With applications ranging from science and exploration to humanitarian and military efforts, the rising need for autonomous vehicles demands constant innovation and growth. The Intelligent Dependable Embedded Architectures (IDEA) lab at the University of Kentucky is continually launching research oriented programs [1]. A few key projects focus on the development of Unmanned Aerial Vehicles (UAV). Through this research, at the University of Kentucky, the need to develop a reliable, lightweight, node based hardware for use in light UAVs and other unmanned and autonomous vehicles became apparent. This paper addresses the design and implementation of a network processing node for light UAVs. This system utilizes a Controller Area Network (CAN) noise tolerant communications bus, a low power ZigBee Wireless Network for expanded inner plane communications and Silicon Laboratories C8051F041 microcontrollers to provide the necessary inputs/output and data processing. The final result will be a flight ready light UAV featuring distributed processing nodes to handle the servo communications and controls

Progress towards a public chemogenomic set for protein kinases and a call for contributions

Protein kinases are highly tractable targets for drug discovery. However, the biological function and therapeutic potential of the majority of the 500+ human protein kinases remains unknown. We have developed physical and virtual collections of small molecule inhibitors, which we call chemogenomic sets, that are designed to inhibit the catalytic function of almost half the human protein kinases. In this manuscript we share our progress towards generation of a comprehensive kinase chemogenomic set (KCGS), release kinome profiling data of a large inhibitor set (Published Kinase Inhibitor Set 2 (PKIS2)), and outline a process through which the community can openly collaborate to create a KCGS that probes the full complement of human protein kinases

Director of Graduate Studies

Over the last decade, research into unmanned and autonomous vehicles has greatly increased. With applications ranging from science and exploration to humanitarian and military efforts, the rising need for autonomous vehicles demands constant innovation and growth. The Intelligent Dependable Embedded Architectures (IDEA) lab at the University of Kentucky is continually launching research oriented programs [1]. A few key projects focus on the development of Unmanned Aerial Vehicles (UAV). Through this research, at the University of Kentucky, the need to develop a reliable, lightweight, node based hardware for use in light UAVs and other unmanned and autonomous vehicles became apparent. This paper addresses the design and implementation of a network processing node for light UAVs. This system utilizes a Controller Area Network (CAN) noise tolerant communications bus, a low power ZigBee Wireless Network for expanded inner plane communications and Silicon Laboratories C8051F041 microcontrollers to provide the necessary inputs/output and data processing. The final result will be a flight ready light UAV featuring distributed processing nodes to handle the servo communications and controls

The promise and peril of chemical probes

Chemical probes are powerful reagents with increasing impacts on biomedical research. However, probes of poor quality or that are used incorrectly generate misleading results. To help address these shortcomings, we will create a community-driven wiki resource to improve quality and convey current best practice

Abstracts of the 22nd International Isotope Society (UK Group) Symposium: synthesis and applications of labelled compounds 2013

Meeting Summary The 22nd annual symposium of the International Isotope Society's United Kingdom Group took place at the Møller Centre, Churchill College, Cambridge, UK, on Friday, 18 October 2013. The meeting was attended by 65 delegates from academia and industry; the life sciences; and chemical, radiochemical and scientific instrument suppliers.Delegates were welcomed by Dr Ken Lawrie (GlaxoSmithKline, UK, chair of the IIS UK group). The subsequent scientific programme consisted of oral and poster presentations on isotopic chemistry and applications of labelled compounds, or of chemistry with potential implications for isotopic synthesis. Both short‐lived and long‐lived isotopes were represented, as were stable isotopes. The symposium programme was divided into a morning session chaired by Dr Karl Cable (GlaxoSmithKline, UK) and afternoon sessions chaired by Mr Mike Chappelle (Quotient Biosciences, UK) and by Dr Nick Bushby (AstraZeneca, UK). The UK meeting concluded with remarks from Dr Ken Lawrie (GlaxoSmithKline, UK)